BioProtocol (BIO) slides in the first hours of trading despite DeSci hype Hristina Vasileva | usagoldmines.com

BioProtocol (BIO) started its trading in the first day of the new year, entering price discovery through its first spot Binance pair. The token started with losses, despite Binance’s popularization of the DeSci space. 

Bio Protocol (BIO) opened its trading on Binance at $0.86, almost immediately sliding to $0.76. The protocol was the latest Binance Launchpad project, which is one of the first major DeSci selections. However, not all Binance Launchpad listings translate into immediate gains. 

The Binance listing offers pairings against stablecoins USDT and FDUSD, as well as Binance’s native token BNB and the Turkish lira. The BIO/USDT pair is the most active and liquid one, driving the asset’s price discovery. Bio Protocol may make its gains after Binance’s special attention. The project drew undisclosed financing from Binance Launchpad, and was then added as a reward token to the Launchpool.

BIO immediately became the leading DeSci token with a market cap of $1.2B and a fully diluted valuation of $2.4B. BIO achieved $338M in its early days on Binance, out of $488M for all other DeSci tokens. 

BIO has seen relatively low decentralized activity, as DeSci tokens are one of the niche categories with low trading volumes. Most of the tokens are a subset of meme tokens, attempting to grow their influence. BIO is the asset with the most prominent listings, while also showing limited DEX swaps. 

On the positive side, BIO is not sniped and there are few signs of connected wallets and active clusters. The token has a clean slate to start from, and become one of the more prominent DeSci assets. 

BioProtocol itself is not dealing with decentralized science, but is a launchpad for DeSci DAOs. The organizations promote their research, while also creating a native token. Before its trading launch on Binance, Bio Protocol helped launch 8 DAOs. 

The BioProtocol DAOs are among the top organizations in DeSci, already building significant treasuries and receiving donations. Hairdao is the leader with $77M in its treasury and is one of the more prominent DAOs. 

BioProtocol aims to become the launchpad for legitimate DeSci projects, to avoid the creation of money-grab tokens. 

DeSci sector rallies on BioDAO effect

DeSci was one of the relatively niche sectors at the end of the last year. The listing of BioDAO and the renewed attention led to vertical growth of overall market capitalization. DeSci startups mostly deal with life extension and biohacking, and are often related to a single task of biological science or drug discovery.

DeSci tokens were valued at around $500M for a long period, before exploding and reaching a total market capitalization of $2.4B. 

The new price action may attract bots and real traders, as there is constant demand for new types of tokens with more upside potential. Out of that new valuation, BIO takes up $1.2B based on its recent price action. 

Previously, most of the attention of the DeSci sector was focused on TRAC, as well as the two tokens of Pump.Science, URO and RIF. Just like in the case of AI agents, the real price action may accrue to platforms for launching new projects, instead to individual projects. The real gains come from mass launches and competition among DeSci features and new tokens. 

The DeSci sector may offer an experience similar to meme tokens, where traders look for a fast turnover, instead of turning into long-term holders. On the other hand, DAOs remain a vehicle for communities to gain from the overall trend, without exposure to any particular asset. 

At the beginning of 2025, DeSci gained exposure on social media, essentially making its debut as a token sector in the past few months. However, most of the tokens are extremely illiquid, and have not gained many of the reliable trading platforms. Hacks related to URO and RIF also undermined the sector’s reliability. Most of the tokens are also waiting their turn as the attention of traders is now on AI agents.

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This articles is written by : Nermeen Nabil Khear Abdelmalak

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